| Category Name | Content |
| Name | Juvederm (Hyaluronic Acid Dermal Filler) |
| Uses | FDA-approved for facial volume restoration, including nasolabial folds, marionette lines, lips, and cheeks. Off-label uses include under-eye hollows and jawline contouring. |
| Route of Administration | Intradermal or subdermal injection. |
| Frequency of Use | Maximum every 3 months for elective patients. Results last between 6–18 months depending on the formulation used. |
| Concentration(s) | Varies by product: - Juvederm Ultra XC: 24 mg/mL - Juvederm Ultra Plus XC: 24 mg/mL - Juvederm Voluma XC: 20 mg/mL - Juvederm Vollure XC: 17.5 mg/mL - Juvederm Volbella XC: 15 mg/mL |
| Maximum Dosage | Max 2.0 mL per session. Max 4.0 mL per 3-month period. |
| Contraindications | • Pregnancy, breastfeeding, or planning pregnancy. • Allergy to hyaluronic acid or lidocaine. • History of severe allergies, anaphylaxis, or autoimmune conditions. • Active skin infections, acne, or inflammation in the treatment area. • History of vascular occlusion, necrosis, or embolism from previous procedures. • Use of blood thinners or immunosuppressive medications. |
| Possible Side Effects | • Common: Swelling, bruising, tenderness, redness at injection sites. • Rare: Vascular occlusion, nodules, granulomas, hypersensitivity reactions. • Severe: Anaphylaxis, arterial embolization, tissue necrosis (requiring surgical intervention). |
| Compatibility With Other Treatments/Drugs | • Safe with: Neuromodulators (Botox, Dysport), most dermal fillers. • Avoid with: Recent laser treatments, chemical peels, or other dermal fillers within the last 3 months. |
| Allergies | Patients allergic to hyaluronic acid or lidocaine should not receive treatment. |
| Administration Time | Injection procedure takes approximately 30–45 minutes, including preparation and aftercare. |
| Dosing/Settings | Start with conservative volume (e.g., 0.5 mL per area) and reassess at follow-up visit. |
| IM/Push (if applicable) | Not applicable; should only be administered intradermally or subdermally. |
| What To Do If Adverse Reaction Occurs | • Vascular occlusion: Stop injection immediately, apply warm compress, massage area, administer hyaluronidase if needed. • Anaphylaxis: Administer epinephrine (0.3 mg IM), call 911, provide airway support. • Granulomas: Refer to dermatology for corticosteroid or 5-FU treatment. • Necrosis: Immediate referral to a specialist for wound care and potential debridement. |
| Additional Documentation Requirements | • Signed informed consent form. • Pre-treatment photos (frontal and side views). • Medical clearance if history of vascular complications, autoimmune disease, or recent oncology treatment. • Documentation of past filler treatments and allergy history. |