| Name | Compounded Glutathione (IV, IM, Oral) |
| Uses | Antioxidant therapy, immune support, detoxification support, skin brightening, adjunctive therapy in chronic conditions. |
| Route Of Administration | Intravenous (IV), Intramuscular (IM), Oral (capsules, sublingual). |
| Frequency Of Use | IV: 1-2 times per week, IM: 1-3 times per week, Oral: Daily as prescribed. |
| Concentration(s) | IV: 200 mg/mL - 2,000 mg/mL, IM: 200 mg/mL - 600 mg/mL, Oral: 250 mg - 1,000 mg per dose. |
| Maximum Dosage (Day, Wk) | IV: Max 2,000 mg per session, up to 2 times per week; IM: Max 600 mg per injection, up to 3 times per week; Oral: Max 2,000 mg per day. |
| Contraindications | Pregnancy, active malignancy, severe asthma, allergy to glutathione components, renal or hepatic failure. |
| Possible Side Effects | Common: nausea, dizziness, flushing. Rare: allergic reaction, respiratory issues (bronchospasm). |
| Compatibility With Other Treatments/Drugs | Safe with most IV therapies; avoid concurrent high-dose acetaminophen or chemotherapy agents without provider review. |
| Allergies | Check for hypersensitivity to glutathione or preservatives in compounded formulations. |
| Administration Time | IV: 15-30 min infusion, IM: 1-2 min injection, Oral: As directed by provider. |
| Dosing/Settings | IV: Start with 600-1,200 mg per session, titrate based on tolerance; IM: 200-600 mg per session; Oral: 250-1,000 mg daily. |
| Test Spot Requirement | Not required for glutathione administration. |
| Pre-Treatment Guidelines | Ensure adequate hydration, rule out contraindications, review GFE for patient eligibility. |
| Provider Clearance Guidelines | NP, PA, MD, or DO must approve; review history of respiratory issues, kidney function, and medication interactions. |
| Pre-Treatment Screening Workflow | 1. Check for asthma, kidney/liver disease. 2. Confirm no active malignancy. 3. Ensure patient understands therapy goals. |
| What To Do If Adverse Reaction Occurs | Mild: Reduce dose or discontinue; Severe: Administer oxygen, antihistamines, and escalate to emergency care if necessary. |
| Clinic Implementation Guidelines | Ensure proper IV/IM preparation, document batch and lot number for compounded doses, follow aseptic technique. |
| Photographic Documentation Protocol | Not required for glutathione therapy. |
| Post-Treatment Care | Encourage hydration, monitor for delayed reactions, schedule follow-ups for efficacy assessment. |
| Additional Documentation Requirements | Signed informed consent, treatment logs, adverse reaction documentation if applicable. |