Amino Acids / Peptides

Name	Amino Acids / Peptides
Uses	Combination of amino acids and bioactive peptides used to support muscle recovery, tissue repair, immune modulation, and metabolic health. Commonly used in wellness IV protocols for recovery after exercise, immune enhancement, skin and collagen support, and overall metabolic optimization.
Route Of Administration	Intravenous (IV)
Frequency Of Use	Typically administered once weekly for general recovery and wellness support. In performance enhancement or recovery protocols, may be given up to twice weekly for 4 to 6 weeks, followed by reassessment. Long-term use should be reviewed every 8 to 12 weeks.
Concentration(s)	Varies based on formulation, typically 2.5% to 10% amino acids combined with peptides at microgram to milligram concentrations.
Maximum Dosage (Day, Wk) (g/mL)/mL	Maximum dose per infusion: 500 mL amino acid/peptide solution. Maximum weekly dose: 1,000 mL. Higher doses are not recommended for elective wellness patients due to nitrogen load and potential renal strain.
Contraindications	Severe renal impairment or dialysis dependency. Severe hepatic impairment. Inborn errors of amino acid metabolism. Active autoimmune flares if immune-modulating peptides are included. Known hypersensitivity to any amino acids, peptides, or formulation components. Pregnancy and breastfeeding unless cleared by OB provider.
Possible Side Effects	Nausea, flushing, headache, or dizziness during infusion. Injection site irritation. Rare: allergic reaction (rash, itching, hypersensitivity). Peptides may have peptide-specific side effects, including temporary fatigue, appetite changes, or skin flushing.
Compatibility With Other Drugs	Generally compatible with normal saline and D5W. Can be combined with vitamins, minerals, and antioxidants in comprehensive wellness IVs, but compatibility should always be confirmed, especially with peptides.
Allergies	Allergy to individual amino acids or peptides is rare, but reactions to preservatives, stabilizers, or peptide carrier solutions are possible.
Administration Time	Typical infusion time: 60 to 90 minutes for full volume infusions. Slower infusion may improve tolerability in sensitive patients.
IV Dosing	For general wellness and recovery: 250 mL to 500 mL IV once weekly. For intensive recovery or performance enhancement: 500 mL IV once or twice weekly for 4 to 6 weeks, followed by reassessment.
IM/Push	Not recommended for IM or IV push administration due to osmolarity and peptide degradation risk. Controlled IV infusion is preferred for safety and efficacy.
What To Do If Adverse Reaction Occurs	1. Stop the infusion immediately. 2. Assess vital signs (blood pressure, heart rate, oxygen saturation). 3. If nausea, flushing, or dizziness occurs, place the patient in a comfortable position and offer oral fluids if tolerated. 4. For allergic reactions (rash, itching, shortness of breath), administer antihistamines and consider epinephrine if severe. 5. If symptoms persist or worsen, arrange for emergency transfer to a higher level of care (call 911 if necessary).